1st Faculty of Medicine Charles University 1st Faculty of Medicine Charles University Department of Gynaecology and Obstetrics
jurbano 25.01.2018

Perinatology centre

Perinatology centre


Perinatology centre of the Department of Gynaecology and Obstetrics, led by prof. MUDr. Antonín Pařízek, CSc., is a tertiary level obstetric and neonatal intensive care unit. Annualy, approximately 4500 births and 500 NICU admissions take place. It serves as a referral centre for the most severe pathologies in pregnancy for the entire Czech Republic. The centre pursues to follow the evidence-based management of pregnancy pathologies.


The workplace has long-term experience with treatment of:

- preterm delivery

- diabetes in pregnancy

- pregnant patients with heart disease

- inflammatory bowel disease in pregnancy

- pregnant patient after organ transplantation


The ongoing research focuses on:

Endocrinology of the fetomaternal unit

The associations between maternal and fetal steroid production to pregnancy pathologies.

Team: Pařízek, Hill, Dušková, Šimják


Reproductive Immunology

The role of maternal immune system (especially T-regulatory cells and complement system) in the development of preterm delivery.

Team: Pařízek, Koucký, Malíčková, Černý, Hrbáčková


Etiopathogenesis of gestational diabetes mellitus

Identification of biomarkers involved in the development of gestational diabetes.

Team: Pařízek, Šimják, Anderlová, Krejčí, Krejčí


Smoking in pregnancy

The negative impact of smoking on the health of the offspring.

Team: Pařízek, Adamcová, Dušková

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